Cirrhosis of the liver 40 years irreversible, but like already compensated cirrhosis of hepatitis B hepatitis patients by taking nucleoside antiviral drugs is possible to reverse. Cirrhosis is mainly due to various causes of liver damage and fibrosis, and pseudo lobe formation, divided into the decompensated and compensated period, usually in the long stones to be, by actively on the cause of treatment. For example, cirrhosis caused by hepatitis B, patients who already have compensated cirrhosis may be reversed by taking nucleoside antiviral drugs, such as tenofovir and lamivudine. However, at present, the course of cirrhosis is relatively long, and it is very likely that it has entered the decompensated stage. Although the condition can generally be improved by controlling the primary disease, it often cannot be reversed. Cirrhosis patients must actively cooperate with doctors to take treatment, and should pay attention to regular review.