Hypertrichosis is a symptom of sympathetic chain syndrome. Skin irritation, such as increased sweating and hypertrichosis, may occur. Sympathetic chain syndrome is a long-standing, insidious clinical syndrome with multiple etiologies. Typical symptoms appear when ganglion damage is severe and compensatory capacity is weakened, and are often delayed and discovered incidentally at autopsy. The clinical manifestations vary depending on the damaged sympathetic ganglion, but all have common clinical symptoms. Such as pain, sensory disturbance, and vascular dysfunction. Many etiologies can cause sympathetic chain syndrome, such as various acute and chronic infections, systemic or local infections, various endogenous and exogenous toxicities, as well as trauma, degenerative spinal diseases, tumors, vascular diseases and chronic irritating lesions. The disease is caused by damage to different sympathetic ganglia, which leads to the corresponding clinical manifestations. Pathologic changes vary depending on the primary cause, with intracellular vacuole formation and fatty degeneration seen in infectious inflammation, accompanied by congestion, edema and infiltration of the ganglion interstitium and surrounding tissues, and ganglion cell necrosis seen in poisoning and sepsis. Improving clinicians’ awareness of the disease and early diagnosis and treatment can effectively relieve clinical symptoms. There is no effective preventive measure for the disease, but the main thing is to find the abnormalities early to the large regular hospital to do the examination and treatment, the more timely the treatment the better the prognosis. The more timely the treatment, the better the prognosis. Usually pay attention to avoid cold, avoid eating cold, spicy and stimulating food, avoid smoking and drinking, eat more egg and milk meat food as appropriate.