The flesh on the side of the toenail, red, swollen and painful, considering the improper size of shoes, overwork and other physiological factors, but also consider trauma, inguinitis, can follow the doctor’s instructions to use medication, surgical treatment and so on. 1. Physiological factors: inappropriate size of shoes, overwork and so on will cause some people’s toenails on the side of the flesh red, swollen and painful. Usually, it is relieved after replacing loose shoes, resting properly and applying ice packs in the early stage and hot packs in the late stage, and no special treatment is needed. 2. Trauma: If the injury is clearly caused by trauma, you can use iodine or 75% alcohol to disinfect it by yourself, and if the trauma is large or serious, you can go to the doctor for debridement treatment. In the early stage, the swelling can be relieved by applying ice packs, and in the later stage, hot compresses can be applied to promote the swelling to subside. 3. Inguinitis: If the symptoms of inguinitis are mild, you can soak your feet in warm water to relieve the swelling and pain. If there is inflammation without abscess, you can use mupirocin ointment, fusidic acid cream and other antibiotic treatment. When there is a local abscess, it is possible to drain the abscess and extract the nail, and take amoxicillin, cefaclor and other antibiotics to prevent infection. It is recommended that toenails on the side of the flesh, red, swollen and painful, clear cause of the treatment in accordance with the doctor’s instructions, do not self-medication or prescriptions. Daily attention to foot care, keep local clean and dry, avoid foreign body friction stimulation.