There are three generations of in vitro fertilization available with genetic myotonic dystrophy. Genetic myotonic dystrophy is a group of hereditary muscle degeneration diseases, mainly manifested as progressive aggravation of symmetrical muscle weakness, muscle atrophy, and eventually complete loss of motor function. Initially, there will be some muscle weakness, and can not normally dominate some activities, and slowly there will be some atrophy or paralysis, there is no cure for this disease. Because this kind of muscular dystrophy may appear hereditary situation, choose in vitro fertilization need to carry out three generations of test tube, will be the embryo before the transfer of genetic testing, choose healthy embryos implantation, avoid the next generation to inherit the disease. Moreover, before carrying out in vitro fertilization, it is necessary to evaluate the woman’s physical condition to ensure the successful completion of the overloaded process of pregnancy. The specific treatment program requires a visit to the hospital to determine the plan for assisted conception under the guidance of the doctor.