Nucleic acid testing is generally referred to as neocoronavirus nucleic acid testing, and the main difference between a nasal swab and a pharyngeal swab for neocoronavirus nucleic acid testing is that they are collected in different locations. Nasal swabs are taken deep in the nose, while pharyngeal swabs are taken deep in the throat. Nasopharyngeal swabs have a higher positive detection rate than oropharyngeal swabs. Nasal swab collection, through the swab to measure the distance from the nostril to the root of the ear and make a mark, the swab from one side of the nostril against the wall of the nostril slowly into the mark to the mark, and then slowly rotate the swab several times and remove it, to test the other side of the nostril the same way, the swab is completely placed in the reagent tube. For pharyngeal swab collection, pass the swab over the base of the tongue and repeatedly wipe the swab over the posterior pharyngeal wall at least 3 times, avoiding contact with the tongue and oral mucosa, etc., when removing it, and then place the swab completely in the tube. Nasopharyngeal swabs have a higher positive test rate than oropharyngeal swabs because the nasal cavity is relatively closed and viruses are more likely to accumulate. However, a pharyngeal swab collection is generally preferred because of the intense discomfort that nasal swabs can cause the subject, as well as the abnormalities of some nasal structures. The exact method of collection to be used needs to be decided by a medical professional according to the actual situation.