Slight hyperplasia of the cardia mucosa is a serious condition, but it can be managed with aggressive treatment and regular review. Cardia hyperplasia is a proliferative disease on the cardia mucosa, which is a more serious condition and may be related to factors such as poor eating habits, food irritation and chronic inflammation. Clinically, it is usually manifested as worsening of dysphagia, nausea, vomiting, weight loss and other symptoms. For cardia mucosal hyperplasia, one can pay attention to the diet and eat less food with high temperature and spicy food. It can also be treated by taking medicines to inhibit gastric acid secretion, such as pantoprazole sodium enteric capsule and rabeprazole sodium enteric tablet as prescribed by the doctor, and going to the hospital for regular checkups. When the patient has a slight hyperplasia of the cardia mucosa, it is recommended to go to the hospital in time to receive professional diagnosis and further treatment. Medications should be used under the guidance of a doctor.