In vitro fertilization downgrading precautions are as follows: 1, the problem of injection: long-acting downgrading injection can be injected once in the hospital, no need to go home for injection; short-acting downgrading injection needs to be injected every day, involving the problem of going home for injection or finding a clinic doctor for injection, some short-acting downgrading injection only needs half a shot per day, it involves the problem of splitting the needle, it is recommended that when injected in the hospital, you can record a small video on your cell phone, learn from the nurse, and go home for easy viewing. 2, bleeding during the process of down-regulation: during the process of down-regulation of the ultra-long program, a small amount of vaginal bleeding may occur for about 5 days, which is not necessary to worry about and does not require special treatment; during the process of down-regulation of the regular long program, normal menstrual flow may occur, lasting about 4-5 days; 3, low estrogen symptoms: during the process of down-regulation estrogen is reduced, some people may have low estrogen symptoms, including hot flashes, dryness, insomnia, weakness If it does not affect personal life, no special treatment is needed; if it seriously affects their work and life, a small amount of estrogen can be supplemented to relieve the symptoms.