The prostate is an important gland in men, mainly located around the posterior urethra, and its main function is to secrete prostate fluid, which is an important component of semen, and prostate fluid plays a vital role in the liquefaction of semen. Lecithin microsomes are an important part of prostate fluid. Common prostate diseases, such as prostatitis, can cause changes in the content of lecithin microsomes. Clinical examination of changes in the content of lecithin microsomes in the prostate fluid is a very important guide to determining prostate diseases. Normal prostate fluid is rich in lecithin microsomes, but a significant decrease in lecithin microsomes can be observed in prostate fluid specimens from patients with chronic prostatitis, which is often indicative of chronic prostatitis.