Stroke is the third most fatal and first most disabling disease worldwide, and in China it is already the leading cause of death and disability. The treatment of stroke in the acute phase remains challenging because it first requires CT to identify hemorrhage or ischemia and has a short time window for treatment. Although the thrombolytic drug t-PA has been shown to be the only effective treatment for acute ischemic stroke, with significant efficacy in both revascularization and clinical symptoms, its low revascularization rate and short time window of application are far from meeting clinical needs. Therefore, endovascular treatments such as mechanical opening have been rapidly developed in recent years. Studies have demonstrated that early revascularization and clinical prognosis are closely related. Revascularization restores blood flow and rescues neurons in the semidark band, thus significantly improving prognosis. Although t-PA and urokinase can achieve revascularization, both intravenous thrombolysis and arterial thrombolysis are still very ineffective for proximal large vessel occlusion, and the time window for clinical application is very short, and there is also the possibility of disrupting the blood-brain barrier leading to complications such as cerebral hemorrhage, so they cannot meet clinical needs and are currently mainly applied to acute ischemic stroke patients with distal small vessel occlusion. In recent years, interventional mechanical devices have shown some advantages, such as balloon and stent shaping and MERCI, PENUMBRA, SOLITAIR AB/FR for embolization, especially for those who are not suitable for drug thrombolysis, ineffective thrombolysis, beyond the time window of thrombolysis, combined with coagulation disorders, hard or calcified thrombus, but for those with tortuous vessels in place, clamping, penetrating branch events However, for tortuous vessels, clotting, penetrating events, embolus fragmentation and embolization of the distal vessels are the shortcomings of the current mechanical devices. The main advantages of interventional mechanical recanalization devices are: rapid opening of occluded vessels, no destruction of the blood-brain barrier, no neurotoxicity, etc. However, unfavorable factors such as high technical requirements for the interventional physician, high price, and increased risk of bleeding also limit the use of interventional mechanical devices in revascularization therapy. Interventional mechanical opening therapy requires the use of an interventional device device to destroy and crush the thrombus or remove the thrombus outside the vessel to achieve the goal of opening the occluded cerebral vessels. Since the clinical effect of arteriovenous thrombolysis is unsatisfactory, the time window is very limited and the current thrombolytic drugs have neurotoxic effects, mechanical recanalization therapy is developing rapidly and the rate of vascular recanalization is greatly improved. The specific devices are: 1, micro guidewire and micro catheter: not a special device for revascularization, mainly used in the early stage, sometimes combined with arterial thrombolysis, mainly using micro guidewire and micro catheter through the site of thrombus occlusion, one can achieve partial revascularization, but can inject thrombolytic drugs into the thrombus to increase the effect of thrombolytic therapy, and then is to provide access for balloon or stent shaping. 2.Balloon and stent shaping: It mainly presses the thrombus or atherosclerotic plaque between the stent and the vessel wall to quickly recanalize the vessel and restore blood perfusion, which can sometimes cause the risk of penetrating occlusion or entrapment. 3.MERCI device: It is mainly a continuous circular device with the head end arranged in a conical shape, together with the use of balloon catheters and special microcatheters, etc. 4.PENUMBRA system: This is a set of aspiration devices dedicated to cerebral artery thrombosis after MERCI. It includes reperfusion catheter, separator, thrombus recovery and negative pressure suction device. 5.SOLITAIRE FR stent: a kind of self-expanding stent dedicated to thrombus retrieval, early more OFF-LABEL using SOLITAIRE AB (dedicated to intracranial aneurysm assisted embolization), the most important feature is retrievable. It is reported to achieve more than 90% revascularization rate, exceeding MERCI and PENUMBRA systems. In practice, for patients who cannot be opened quickly, multiple opening techniques are often used, such as combined arteriovenous thrombolysis, combined application of mechanical retrieval or balloon angioplasty, stent retrieval or even permanent stent implantation.