Closed pore acne, also known as closed mouth, has many removal methods in the clinic, mainly medication, needle clearing treatment and so on. 1. Medication: Patients with more closed-cell acne can choose topical medications, such as Vitamin A cream and Adapalene gel, which can effectively improve acne. If the closed-cell acne is relatively small, it is not convenient to apply the drug, you can choose oral medication, common drugs are viamin ester capsule, isotretinoin capsule, with the role of regulating cellular keratinization. The medication should be used according to the doctor’s instructions. 2. Needle clearing treatment: closed pore acne can also choose the needle clearing treatment, generally suitable for a small number, but the acne is relatively large, can effectively remove the secretion of acne. Closed-cell acne treatment methods are mainly the above, due to individual differences, it is recommended to combine the individual’s situation, under the guidance of the doctor to choose some appropriate treatment methods.