First, some necessary tests should be perfected to clarify the benignity and malignancy of the nodules as early as possible. Malignant nodules should be operated promptly. Most benign nodules can be examined regularly. Since ultrasound results can be affected by the examining doctor and equipment, it is best to have the same ultrasound doctor for each review and to keep the results of previous examinations for the doctor’s comparison. In some cases, surgery and radioactive iodine treatment may be an option for benign nodules, such as nodules that are clearly pressing on surrounding organs and causing discomfort, or a nodule known medically as a “thyroid adenoma” that is affecting the normal function of the thyroid gland. Some people do not need special treatment for benign nodules, but they always feel uncomfortable with a “little thing” on their neck, so they often ask if there is any medicine that can make the nodule shrink and disappear. The main medication currently used to treat thyroid nodules is levothyroxine (such as eugenol), but it is not very effective. Also, because of the relatively high dosage of medication, it may lead to subclinical hyperthyroidism, causing discomfort such as panic, chest tightness, and insomnia. Postmenopausal women are also prone to osteoporosis if they take the medication for a long time. Weighing the pros and cons, doctors generally do not recommend treatment for patients.