The disadvantages of titanium alloy repair of the skull, the skull as the protective layer of the brain, maintaining the normal activity of brain tissue, so that our body functions normally, skull defects are very terrible, will make the patient have localized swelling and pain, but also cause varying degrees of dizziness, headache, memory loss, self-control, and other symptoms, the more serious will cause brain tissue atrophy and cystic degeneration. Based on this danger, cranial defects must be repaired, and the right repair material must be selected to ensure postoperative recovery. At present, the most widely used repair material is titanium alloy, so many patients can’t help but have questions, titanium alloy repair of the skull has disadvantages, will rust? Some experts answered: it won’t rust, but there are still many disadvantages and shortcomings of using titanium alloy as the material for repair. For example, patients are particularly sensitive to hot and cold reactions after the operation, not daring to sunbathe, there is some slight pain in the edge of the repair, patients can not accept normal medical examination after the operation, and at the same time, the appearance of the effect can not make the patients satisfied. In order to let more patients with cranial defects see the hope of perfect repair, after unremitting efforts, after in-depth exploration, through clinical practice has proved that a new type of material – polyether ether ketone material, also commonly known as PEEK material in the cranial bone as a material for repairing its uniqueness and advancement of its insulation, strength, hardness, elasticity, etc. are the same as the autologous cranial bone, but also the same as the autologous cranial bone. Its heat insulation, strength, hardness, elasticity, etc. are comparable with the autologous skull, and it perfectly restores the anatomical technology of the skull through 3D printing technology, and carries out complex molding, so that it fits perfectly with the edge of the patient’s defects, with excellent cosmetic effect. The application of Peek material is exactly the latest trend in cranial bone repair.