Generalized pain may be related to sudden strenuous exercise, infectious diseases, severe anemia, insufficient blood supply to the brain and other factors. 1. Sudden and strenuous exercise: if you lack of exercise, sudden and strenuous exercise will easily lead to an increase in lactic acid in the body, causing excessive accumulation of lactic acid in the muscles or joints, resulting in generalized muscle pain and generalized discomfort. 2. Infectious diseases: when patients suffer from pneumonia, upper respiratory tract infection, acute gastroenteritis and other diseases, the body is infected by bacteria, viruses and other pathogens, resulting in generalized discomfort. 3. Severe anemia: due to the decrease in the content of red blood cells in the blood, the ability of the blood to carry oxygen is significantly reduced, resulting in chronic hypoxia of the brain, dizziness, pallor, fatigue and other symptoms, manifesting generalized distress. 4. Insufficient blood supply to the brain: If the blood supply to the vertebral basilar artery or internal carotid artery of the brain is insufficient, it may lead to dizziness, headache and other symptoms, and generalized discomfort. Patients with generalized discomfort should go to the hospital as soon as possible to get a clear diagnosis of the cause of the disease and then give the correct treatment under the guidance of the doctor.