Frequent sleep symptoms of panic and shortness of breath, first consider the existence of cardiac insufficiency, but also need to rule out the existence of respiratory sleep apnea syndrome. 1. Cardiac insufficiency: when the patient develops cardiac insufficiency, lying down due to the increase in the volume of returned blood, the burden on the heart increases, and the lungs also have the symptom of stagnation, panic and shortness of breath will occur, which needs to be treated according to the patient’s clinical symptoms, combined with the examination of cardiac ultrasound. If cardiac insufficiency is found, oral spironolactone, β-blockers, sartans or prilosec drugs need to be taken under the guidance of the doctor to treat it and slow down the development of heart failure. 2. Respiratory sleep apnea syndrome: when the patient has respiratory sleep apnea syndrome, it will also lead to the above symptoms, because the tongue falls back when lying down, so there will be chest tightness, and it is recommended to consult the otorhinolaryngology department of the regular hospital. When lying down and sleeping with panic and shortness of breath, first of all, cardiac insufficiency should be excluded, and it is recommended to consult the cardiovascular internal medicine department of regular hospitals.