For middle-aged and elderly people, knee pain, swelling and, in severe cases, painful walking up and down stairs and inability to bend are often the cause of dysfunction. The following is my opinion on the treatment of osteoarthrosis of the knee. First of all, the treatment of osteoarthrosis of the knee should be based on age. If the age is older than 65 and the joint degeneration is serious, it is recommended to choose joint replacement first, so that the function can be restored as soon as possible, which can significantly improve the quality of life of the elderly and help to restore their self-confidence and improve their social identity. It also reduces the occurrence of fractures in other parts of the body due to falls caused by difficulty in walking. For elderly people younger than 65 years old but older than 50 years old, if the MRI diagnosis of osteoarthrosis of the knee joint belongs to articular cartilage degeneration grade III or less, intra-articular injection of sodium vitreous acid, coupled with reduced activity, attention to warmth, with oral glucosamine and non-steroidal painkillers, most of the symptoms can be relieved; if the MRI report of articular cartilage degeneration is greater than grade III, consider taking Arthroscopic surgery can be considered to clean up the degenerated meniscus and cartilage. Secondly, for patients with inversion of the knee (O-leg), if the combined medial tibial articular cartilage degeneration reaches grade III or higher and the patient is younger than 60 years old, surgical intervention is recommended to correct the inversion deformity and adjust the joint force lines by internal or external fixation, which may allow the patient to maximize joint function while delaying or even avoiding joint replacement surgery. For patients over 65 years of age who have an inversion deformity of the knee combined with articular cartilage degeneration exceeding grade III, joint replacement is the best option so that joint function can be restored as soon as possible. In conclusion, degenerative osteoarthrosis of the knee needs to be taken seriously from the inside and must be treated as actively as conditions permit.