Hashimoto’s disease generally refers to Hashimoto’s thyroiditis. Hashimoto’s thyroiditis is a chronic autoimmune disease of the thyroid gland that may be characterized by the presence of antibodies against thyroid antigens in the serum and thyroid tissue due to a disruption of the body’s immune tolerance, and is characterized by a lymphocytic infiltration of the thyroid tissue. Blood tests in patients with Hashimoto’s thyroiditis reveal markedly elevated serum levels of thyroid peroxidase antibodies (TPOAb) and thyroglobulin antibodies (TgAb). Most patients with Hashimoto’s thyroiditis have enlarged thyroid glands, mostly diffuse. Lesions often involve both glands. The thyroid gland is hard and rubbery, and the surface is usually flat. There is no adhesion to the surrounding tissues and it can move up and down with swallowing. Patients with Hashimoto’s thyroiditis are advised to visit a hospital and ask their doctor for a consultation.