Glans erosion may be related to glans circumcision, drug rash or lichen planus, etc. Specific medication needs to be selected according to the condition, including local topical medication and internal antifungal and anti-allergic medication. 1. glans penis: localized erosion and oozing can be sterilized with iodophor solution, and apply antibiotic cream such as erythromycin cream, etc., for candida infection can be treated with itraconazole, and anaerobic infection can be treated with metronidazole. 2. Drug rash: such as fixed-type drug rash, can occur in the oral cavity, genital area, can cause erosion and oozing. Need to stop the use of sensitizing drugs, drink more water or intravenous fluids to accelerate the discharge of drugs, can be given antihistamines such as benadryl, vitamin C and calcium, if necessary, give a small dose of prednisone, the local can be indirectly wet compresses. 3. Lichen planus: when the glans is involved, there are white reticular stripes, which can be enlarged and eroded, and can be treated with topical glucocorticosteroids, tacrolimus or vinblastine cream, or local glucocorticosteroids can be closed. Erosion of the glans may also be caused by other reasons, it is recommended to go to the hospital specialist in a timely manner, to clarify the cause of the disease and follow the doctor’s instructions for treatment, the drug should be applied under the guidance of the doctor.