Closed mouth acne around the mouth can be removed by maintaining good lifestyle habits, topical creams, oral medications, and physical methods. Closed mouth pimples, also known as closed pimples and whitehead pimples, is a common type of acne lesions, mainly small pimples of the size of a needle tip to a pinhead, occurring in seborrheic areas of the skin. 1. Maintain good habits: Pay attention to cleanliness, use warm water and neutral soap to clean the face to reduce the oil attached to the face to block the pores. Avoid squeezing and scratching acne with hands. Avoid spicy and irritating foods. Keep bowel movement smooth, avoid staying up late. 2. Topical medications: benzoyl peroxide, 5% to 10% salicylic acid cream, retinoids (such as retinoic acid gel, adapalene gel, etc.) have the effect of dissolving keratin and removing acne. 3. Oral medication: If the effect of topical medication is not good or the lesion area is large, oral retinoids such as isotretinoin can be combined. 4. Physical therapy: In addition, you can also use intense pulsed light and other physical methods to remove closed mouth acne. If you need to use medication in case of closed mouth acne, you should be treated under the guidance of a professional physician, and should not treat it on your own, resulting in adverse consequences.