The mosquito bite swollen very badly and very painful, need to go to the hospital for blood tests to see if there is a combination of bacterial infection. If the blood inside the white blood cells and neutrophils are not high, need anti-allergy treatment, commonly used anti-allergy drugs are loratadine tablets, cetirizine tablets, olopatadine tablets and other antihistamines, as well as vitamin C and calcium gluconate. If necessary, glucocorticosteroids can be taken orally or ordered quietly, and topical medications can be used such as glucocorticosteroid creams like Denide cream and mometasone furoate cream. If the blood inside the white blood cells and neutrophils are high, then the combination of bacterial infection is considered, then in addition to the above anti-allergy treatment, you also need to add antibiotics, such as cephalosporin, roxithromycin and so on, usually pay attention to prevent mosquito bites.