A positive carbon 13 urea breath test is indicative of H. pylori infection in the stomach. The prevalence of infection in the normal population should be above 50%, and there are symptoms, including nausea, vomiting, acid reflux, belching, and indigestion such as abdominal distention. In addition there is a correlation between peptic ulcers or digestive tract tumors, and malignant lymphoma of the stomach with H. pylori infection. At present, it is recommended that H. pylori infection should be sterilized, the current recommended treatment plan is quadruple therapy, mainly two antibiotics, plus an acid-suppressive drugs, plus a bismuth, oral 14 days, 14 days after the drug is stopped, one month after the drug is stopped again to review, to understand whether the sterilization success.