Parkinson’s patients can experience fluctuations in symptoms throughout the day, primarily related to the end-of-dose phenomenon of medication. However, this fluctuation is different from the typical morning light and evening heavy performance of myasthenia gravis. Parkinson’s disease patients appear to take levodopa drugs, symptoms have rhythmic fluctuation phenomenon, shortly after taking the drug symptoms are the lightest, a few hours later, the symptoms gradually aggravated, until the next levodopa dose, the symptoms and then reduce. This is called the end-of-dose phenomenon. Most patients begin to experience this fluctuation of symptoms 1 to 3 years after taking the medication. Parkinson’s patients may exhibit slowed movement, may have a resting tremor, difficulty getting up and falling easily, a blank expression, and a panicked gait. There may be anxiety, depression, easy irritability and emotional instability. There may also be constipation and poor urination. Parkinson’s patients should eat a light diet, avoiding too much overly oily food. Not eating fatty meats and animal offal will help prevent the harmful effects of excessive intake of saturated fat and cholesterol on the patient’s body. Spicy foods should not be eaten. Because most Parkinson’s patients suffer from constipation, and spicy foods can cause constipation to worsen, avoid foods that can cause constipation.