The feeling of ants crawling on the legs is caused by inflammatory infection and is a sensory disorder that can be treated with vitamin B to nourish the nerve ends. In the later stages of diabetes, it can also cause similar symptoms and requires prompt glucose-lowering treatment to keep blood sugar under control and control the cause as much as possible. At the same time, the affected limb is treated with decompression to avoid pressure sores, and debridement and negative pressure drainage are performed to ensure the integrity of the limb. Patients can soak their feet in warm water to promote blood circulation, stabilize the condition, and help restore the blood vessels and nerves in the affected limb. Hypothyroidism can also cause similar symptoms, which are caused by rough skin due to lower metabolism. The primary condition should be treated promptly, and levothyroxine should be used to increase the hormone content and promote recovery to avoid inflammation of the thyroid gland.