Heart disease can have a very obvious effect on all organs and systems of the peripheral organs. 1. If a patient has a history of heart disease, it will have the greatest effect on the circulatory system, and the patient will suffer from insufficient circulatory blood supply, and will have obvious chest tightness, shortness of breath, palpitations, precordial pain, discomfort in the precordial area, accompanied by peripheral weakness and difficulty in breathing. 2. An obvious history of heart disease will also have an effect on the digestive system, and the patient will experience nausea, acid reflux, heartburn, vomiting, loss of appetite, poor appetite, etc. 3. Patients with severe heart disease can have an impact on the nervous system, such as dizziness, headache, blurred vision, vertigo, transient blackouts, or transient loss of consciousness. 4. Severe heart disease can also have an impact on the kidneys, causing chronic renal insufficiency.