The causes of high glutamyltransferase are both physiologic and pathologic. Physiologic causes include fatigue, late night, alcoholism, etc. Pathologic causes include viral hepatitis, parasitic infections, drug liver damage, cirrhosis and so on. 1. Lifestyle and dietary causes: such as fatigue, late night, alcoholism, etc., the general value will not be higher than three times the normal value, and can be restored after removing the triggers. 2. Disease causes: common symptoms include jaundice, loss of appetite, edema, abdominal distension and so on. For example, viral hepatitis can have abnormal viral series, abnormal liver function, etc.; for parasitic infection, there can be abnormal stool routine, abnormal hepatobiliary CT, etc.; medication liver damage has a history of taking medication; cirrhosis can have abnormal liver fibrosis, abnormal coagulation, etc. If glutamyltransferase is high, it is recommended to consult the doctor and analyze the cause of the disease with the combination of personal situation and necessary auxiliary tests.