Glucosamine is a drug that needs to be taken for at least 1-3 months to have a significant effect. The main mechanism of action of glucosamine sulfate or glucosamine hydrochloride is to promote the formation of cartilage matrix by replenishing the nutrients needed for its formation and to inhibit its destruction. The duration of action of these drugs is relatively long, so patients with related injuries should use them early in their treatment. If there is no effect after a period of use, it is important to return to the orthopedic department for a timely follow-up and adjustment of the treatment plan. In addition, patients should not blindly expand the indications for these drugs, which are mainly used for some injuries to the synovial membrane and hyaline cartilage inside the joints, which are commonly seen in the knee, shoulder and hip joints. If the patient has a spinal fibrocartilage injury, such as a herniated disc, taking this type of drug is not effective.