The use of Minoxidil does not usually lead to enlarged pores, which may be related to overproduction of sebaceous glands. Common adverse reactions to minoxidil are increased heart rate, weight gain, hair growth, and headache. It does not usually cause patients to develop enlarged pores. It is contraindicated in patients who are allergic to minoxidil and in patients with pheochromocytoma. Enlarged pores may be related to the sebaceous gland secretion, when eating too much greasy food, irregular work and rest, excessive use of electronic products, or long-term use of glucocorticoids, due to excessive sebaceous gland secretion, resulting in secretion clogging pores, pores will gradually enlarged. It is recommended that patients have a regular routine, eat a light diet, avoid eating fried food, and avoid smoking and drinking. Reduce the use of electronic products and stay up late at night. Wash your skin every morning and evening with a gentle cleanser. If the phenomenon of enlarged pores is serious, the patient can be in the regular hospital for laser treatment and other ways to relieve, do not use private medicine, so as not to cause danger.