The heavy odor of urine may be caused by physiological factors, proteinuria, urinary tract infections and so on. 1. physiological factors: the process of urine production, and the bladder storage time is too long, too little water, the bladder mucosa has a weak reabsorption function, so that the concentration of urine is aggravated, which will have a heavy urine odor. 2. Proteinuria: this disease is mainly caused by various primary and secondary renal pathologies resulting in abnormal renal filtration function, resulting in patients with heavy urine odor. 3. Urinary system infection: due to the pathogenic bacteria through the upward infection, bloodstream infection, direct infection, etc., will lead to the patient to appear in the situation of heavy urine odor, accompanied by frequent urination, urinary urgency, urinary pain and other symptoms. It is recommended that patients go to the hospital in a timely manner, under the diagnosis of the doctor, according to the patient’s condition, the line of targeted treatment, life should drink more water, pay attention to the perineum clean, appropriate exercise.