There are many factors for the appearance of ulcers on the feet, the most common being fungal infection resulting in vesicular exudative foot odor, which appears in the vesicular area with obvious fluid exudation and intense itching, with the degree of itching at night being more pronounced than during the day. After the foot is stimulated by trauma, after disinfection treatment also prone to ulceration phenomenon belongs to bacterial infection, diabetes caused by diabetic foot will also appear lower limb ulceration, each cause of ulceration treatment, the method is different. For fungal infections, only topical sertaconazole nitrate ointment should be used for treatment, and for ulcers caused by trauma, antibiotics such as penicillin or cephalosporins should be used for treatment. Diabetic foot caused by diabetes requires glucose-lowering treatment at the endocrinology department.