If it is determined that you have liver disease, the first rule of medical advice is to stop drinking. Some patients do not understand what liver disease has to do with alcohol. Why can’t you drink alcohol if you have liver disease? As we all know, the main component of alcohol is ethanol. After drinking alcohol, it is quickly absorbed in the gastrointestinal tract and only 2% to 10% is excreted from the kidneys, while more than 90% of ethanol is metabolized in the liver and becomes acetaldehyde through cytoplasmic ethanol dehydrogenase catalyzed by the liver cells. Both ethanol and acetaldehyde have toxic effects that directly stimulate and damage liver cells, causing degeneration and necrosis of liver cells. In normal people, ethanol and acetaldehyde can be metabolized and detoxified by the liver after a small amount of alcohol consumption and generally do not cause liver damage. However, one-time heavy drinkers often have symptoms of acute alcoholism such as inadequate diet and vomiting; and in long-term alcoholics, the toxicity of ethanol and ethanol frequently affects the normal metabolism and detoxification of sugar, protein and fat by the liver, leading to serious liver damage, fatty liver and alcoholic cirrhosis. For patients with hepatitis, the substantial damage to the liver causes a decrease in the detoxification function of the liver, which often reduces the activity and secretion of various enzymes required for alcohol metabolism. The liver’s ability to detoxify alcohol is seriously affected, leading to the prolonged course of hepatitis, aggravated, and even the development of cirrhosis or severe hepatitis. It is common to see early hepatitis patients misdiagnosed as “cold” and “weakness”, and then develop into severe hepatitis after eating “fried wine eggs with hanging noodles” or “dried cuttlefish in wine stew”. “There are also reports of chronic hepatitis causing chronic hepatitis activity, rapid rise of transaminases and jaundice due to continuous excessive alcohol consumption or even one large amount of alcohol consumption; long-term alcohol consumption in people with long-term hepatitis B surface antigen positivity is likely to cause cirrhosis and promote cirrhosis loss. Long-term alcohol consumption in people with long-term hepatitis B surface antigen positivity is likely to cause cirrhosis and promote cirrhosis failure, and even promote liver cancer and shorten life expectancy. In conclusion, alcohol is like a big poison for hepatitis patients, which is harmful but not beneficial. For all hepatitis patients, a strict ban on alcohol consumption should be considered a basic self-care measure.