The difference between recombinant human interferon α1b and α2b is that there is a difference in the indications, in addition there may be some difference in price. Recombinant human interferon α1b is mainly used for the treatment of viral diseases and certain malignant tumors, mainly for the treatment of chronic hepatitis B, chronic hepatitis C and hairy cell leukemia, and it is also effective in the treatment of viral diseases such as condyloma acuminatum, chronic cervicitis, herpes zoster, epidemic hemorrhagic fever, viral pneumonia and so on. Recombinant human interferon alpha 2b can be used for the treatment of chronic hepatitis B, chronic hepatitis C, chronic hepatitis D, laryngeal papilloma, hairy cell leukemia, chronic myeloid leukemia, thrombocythemia, and multiple myeloma. The price of recombinant human interferon alpha 2b will be a bit higher than that of alpha 1b. Both are antiviral drugs, and it is recommended that they be used under the guidance of a specialist, not on their own.