Three high refers to high blood pressure, high blood fat, high blood sugar, lower three high can be through the life of dietary regulation, taking antihypertensive drugs, blood fat drugs, blood sugar drugs for treatment, there is no most effective way. 1. Dietary management: quit smoking and drinking; appropriate physical exercise; low-salt, low-fat and low-sugar diet. 2. Antihypertensive drugs: valsartan, hydrochlorothiazide, metoprolol, nifedipine and other antihypertensive drugs can be reasonably used for treatment. 3. Lipid-lowering drugs: commonly used drugs are simvastatin, atorvastatin, fenofibrate, niacin and so on, which can lower cholesterol and triglyceride. 4. Hypoglycemic drugs: commonly used drugs include metformin, glipizide, acarbose, pioglitazone, selegiline, etc., which can effectively control blood sugar. The above drugs have different degrees of adverse reactions, when using these drugs for treatment, must be strictly in accordance with the doctor’s instructions under the guidance of the doctor.