Low total cholesterol may be related to insufficient dietary intake and liver disease, which can be treated by nutritional supplementation and medication. Unbalanced diet and low cholesterol intake in daily life can lead to low total cholesterol, which is mainly seen in people who have lost weight and become vegetarians for a long period of time. At this time, it is only necessary to reasonably match the daily diet and supplement the cholesterol needed by the human body, for example, animal offal, eggs and other foods. Liver diseases such as viral hepatitis can also lead to low total cholesterol, viral hepatitis when liver cells are severely damaged, may cause cholesterol synthesis disorders, which leads to a decrease in total serum cholesterol. Common therapeutic drugs include lamivudine, interferon, and famciclovir, which are mainly used for antiviral therapy. Patients with end-stage hepatitis are mainly treated by liver transplantation. If the total cholesterol is found to be low, you should consult a doctor in time and take treatment under the doctor’s guidance, do not take medication without authorization, so as to avoid delaying the condition. Pay attention to rest on weekdays, quit smoking and drinking, and keep a regular routine.