Trigeminal neuralgia does not cause lymph enlargement, if lymph enlargement occurs it may be caused by other diseases such as tonsillitis or acute pharyngitis, it is recommended to seek medical attention to identify the cause. Trigeminal neuralgia is a kind of episodic pain in the area innervated by the trigeminal nerve. It can be categorized into primary and secondary. Primary trigeminal neuralgia is often explained by vascular compression, i.e., the pain is triggered by the compression of the trigeminal nerve by the superior cerebellar artery and the anterior inferior cerebellar artery with the corresponding vein. Secondary trigeminal neuralgia may be caused by tumors in the brainstem, demyelinating disease, cavernous disease and so on. The clinical manifestations of trigeminal neuralgia are sudden lightning-like burning pain, severe and unbearable pain involving the face, upper and lower jaws or tongue. The pain can be triggered by washing the face, brushing teeth, talking or eating. Episodes last for seconds and minutes with normal intervals. There is no clinical phenomenon suggesting that trigeminal neuralgia causes lymphocele. Primary application of microvascular decompression has good efficacy, secondary root treatment of the cause of the disease, can use carbamazepine, oxcarbazepine and other pain medication; can also be selected according to the situation of radiofrequency thermocoagulation temperature control therapy, trigeminal nerve microvascular decompression, trigeminal nerve rhizotomy and other treatments, the specific treatment follow the doctor’s instructions.