Most of the stage II lung adenocarcinomas require chemotherapy after surgery. The treatment options for stage II lung adenocarcinoma include surgical resection, mainly anatomical lobectomy and hilar mediastinal lymph node dissection, which need to be formulated according to the specific conditions of patients. Moreover, patients with stage II lung adenocarcinoma also need to undergo platinum-containing double-drug regimen for adjuvant chemotherapy after surgery, such as cisplatin and carboplatin, which can promote the elimination of residual tumor cells and reduce the chances of proliferation and metastasis. Therefore, most patients with stage II lung adenocarcinoma need chemotherapy after surgery. Besides, patients who are not suitable for surgery can also be treated with radiation therapy and synchronized radiotherapy. Patients diagnosed with stage II lung adenocarcinoma should actively cooperate with doctors for treatment.