It is not absolutely true that multiple lung nodules are safer, although some multiple lung nodules are consistent with benign disease on imaging and may be safer; however, multiple lung nodules may also have malignant features and are not safe at this time. 1. Multiple lung nodules are relatively safe: multiple lung nodules sometimes have some typical benign features, such as multiple nodules along the bronchovascular bundles, accompanied by the bud sign, etc., which suggests that infectious lesions are more likely and may be safer. 2. Multiple lung nodules are not safe: some multiple lung nodules do not have the pattern of benign features, even if they are accompanied by the history of malignant tumors in other parts of the body, which are mainly distributed peripherally with multiple nodules of different sizes, the possibility of metastatic carcinoma of the lung needs to be considered; there are also some multiple lung nodules that are in line with the characteristic of malignant tumors with corn-like metastasis, which is not safe under the above mentioned circumstances. In conclusion, the number of lung nodules is not of great value in determining the benign or malignant nature of lung nodules, which should be evaluated by the physician with the specific imaging features of the lung nodules.