Uric acid-lowering drugs and statins belong to two categories of drugs, different roles, no contraindications, the use of no conflict, the specific use of medication is recommended to consult a doctor. The main role of statin drugs is to regulate lipids, lower cholesterol, etc., should not be with cyclosporine A, fibric acid derivatives (beta drugs), erythromycin, clarithromycin, colchicine, hepatitis C protease inhibitors, HIV protease inhibitors, niacin, or imidazole antifungal drugs taken at the same time, may increase the risk of myopathy. Excluding uric acid-lowering drugs, there is no conflict between the two. Uric acid-lowering drugs mainly include inhibit uric acid production and promote uric acid excretion of two categories, inhibit uric acid production drugs such as febuxostat to avoid and azathioprine or mercaptopurine, should not be with theophylline, cytarabine, cytotoxicity of the chemotherapeutic drugs, such as the combination of drugs. Promote uric acid excretion drugs such as benzbromarone should not be combined with salicylates, benzosulphonazole ketones, pyrazinamides and other potentially hepatotoxic drugs, and with coumarin anticoagulants need to pay attention to the patient’s prothrombin time. At present, no side effects have been found between uric acid-lowering drugs and statins, and there is no conflict between the two. It is recommended to use uric acid-lowering drugs and statins under the guidance of a professional doctor.