α1-antitrypsin deficiency is an inborn metabolic disease caused by deficiency of the blood antiprotease component, α1-antitrypsin (abbreviated as α1-AT), which is inherited through autosomal inheritance. Clinically, it often leads to neonatal hepatitis, cirrhosis, hepatocellular carcinoma and emphysema in infants and adults. At present, there is no specific treatment, and the commonly used treatments include general treatment, surgery and so on.
1. General treatment: Hepatoprotective treatment to reduce hepatocellular damage, delay liver function loss and slow down the process of a1 antitrypsin deficiency. Alcohol should be strictly prohibited, avoid unnecessary drugs, reduce the metabolic burden on the liver. Eat easily digestible food, often eat vegetables and fruits.
2. Surgical treatment: With liver transplantation, the synthesis, metabolism, secretion and other functions of the liver can be improved, and the a1 antitrypsin deficiency can be relieved.
The a1 antitrypsin deficiency is caused by genetic abnormality, and there is no specific treatment method yet.