Heat rash can be treated with general treatment, topical medication and oral medication. 1. General treatment: prickly heat usually subsides on its own after the skin cools down, pay attention to the indoor temperature, wear loose, soft and breathable clothes. 1. Topical medication: The topical medications commonly used for this disease include glycerite lotion, mometasone furoate cream, etc. These medications can play the role of anti-itching, cooling and astringent. In addition, if the patient is infected, may also need to use erythromycin ointment or fusidic acid cream. 2. Oral medication: For those who have obvious itching symptoms, oral antihistamine medication can be taken, such as cetirizine, loratadine, etc. The combination of severe infections may also require the use of erythromycin ointment or fusidic acid cream. For those with serious infections, oral antibiotic medication is also needed, such as erythromycin and cefradine capsules. If the symptoms of heat rash are significant, it is recommended to use medication under doctor’s guidance in time to avoid further aggravation of the condition, resulting in serious consequences. Drugs should be used under the guidance of a doctor.