How many years can a patient live with targeted cancer drugs is usually related to the progression of the disease, the effect of the drugs, and the patient’s mindset, and cannot be generalized. After cancer patients are treated with targeted drugs, the survival period of some patients can be extended by 1-4 years. Combined with the development of the patient’s disease and the effect of drug treatment, the survival period of some patients can even be extended by decades or long-term survival. For example, patients in the early stage of cancer, the tumor is relatively limited, has not yet metastasized, genetic testing has found the existence of corresponding targets, part of the patients after surgical treatment and then through targeted drug therapy, the prognosis is good, some patients can even survive for a long time until natural death. Some patients may develop tolerance to targeted drugs during the treatment period, and the corresponding survival period may be shortened, and the degree of shortening is related to the development of their own disease. At present, the commonly used targeted drugs include gefitinib, ositinib, sorafenib and so on. Patients need to follow the doctor’s instructions to standardize the use of medication, do not take medication on their own, and at the same time to ensure a positive and optimistic treatment mentality, for the recovery of the treatment is helpful.