Blisters on the feet of bedridden elderly people can be treated by general treatment, medication and other methods, but due to the causes of blisters on the feet of bedridden elderly people are more causes, such as: contact dermatitis, athlete’s foot, atherosclerosis, and so on, the specific treatment needs to be selected according to the cause of the disease. 1. Contact dermatitis: attention should be paid to the clean and dry skin of the affected area to reduce local friction. You can choose to use hydrocortisone cream, mometasone furoate cream, etc., oral loratadine, cetirizine and other drugs for treatment under the guidance of professional doctors. At the same time, we should pay attention to avoid contact with suspected allergens and irritants. 2. Tinea pedis: you can choose to use miconazole cream, terbinafine cream, etc. under the guidance of a professional doctor, if the effect of external drugs is not good or the area of lesions is large, you can take oral itraconazole capsule, terbinafine tablets and other drugs for treatment. 3. Atherosclerosis: Lifestyle should be improved in time with reasonable diet. Choose to use aspirin enteric-coated tablets, atorvastatin calcium tablets and other drugs for treatment under the guidance of doctors. The use of drugs should be standardized under the guidance of a professional doctor. If there is any adverse reaction, you should go to the hospital for examination in time, and carry out standardized treatment as early as possible to avoid causing other symptoms.