Congenital megacolon is the result of the absence or reduction of ganglion cells in the intermuscular plexus of the distal colon and rectal wall, which causes the loss of normal peristaltic function of the intestinal canal, resulting in twin stenosis and the gradual expansion and hypertrophy of the proximal intestinal canal, resulting in megacolon. The main manifestations are long-term constipation, abdominal bulging, and low-level intestinal obstruction symptoms. The rectum is empty in the jug abdomen, and the rectal finger examination can stimulate the defecation reflex, and a large amount of feces and gas can be expelled. After the diagnosis is confirmed, radical surgery of megacolon should be performed. 1, psychological guidance This disease because of the long preoperative intestinal preparation time, most children are infants and children, and economic consumption, large surgery, postoperative may appear abnormal performance, such as: early postoperative daily bowel movements increased, up to more than ten times, and other problems, should be explained to parents in detail, so that they are prepared, face the disease, to obtain cooperation, early treatment. 2. Diet Before the operation, parents are advised to provide the child with a liquid, easily digestible, high-calorie, high-protein, high vitamin-free diet to reduce the formation of feces and enhance the body’s resistance to tolerate the operation. In case of severe malnutrition, correct malnutrition. 3, actively cooperate with the medical staff daily with warm saline clean enema to reduce abdominal distension, excretion of feces, reduce the absorption of intestinal bacteria and toxins. Choose a soft, thick and thin tube during the enema, be gentle, slow enema speed, gently massage the abdomen, repeat the enema, discharge the liquid and the infusion basically match to prevent water poisoning. Pay attention to keep warm to prevent cold. 4, close observation of changes in the condition, such as abdominal distension sharply aggravated, high fever, vomiting, diarrhea, general ‘condition suddenly deteriorated, may be complicated by small intestine colitis, immediately report to the medical staff for rescue. 5, preoperative oral antibiotics and vitamin K injection according to medical advice to prevent postoperative intestinal infection and bleeding, the day before surgery to place the gastric tube and properly fixed, to prevent prolapse.