The need for chemotherapy after surgery for ground glass nodules in the lungs depends on the nature of the pathology of the nodule; if it is malignant, chemotherapy is required. If it is benign, it is not required. There are two types of ground-glass nodules in the lungs, one is pure ground-glass nodules, which have a lower chance of becoming cancerous and are partly caused by inflammation in the lungs, and this type of nodule does not usually need chemotherapy after surgery if the pathology is clearly benign. Some of these nodules are caused by inflammation of the lungs. If the pathology of these nodules is benign, chemotherapy is usually not needed. The second type is mixed pulmonary ground-glass nodules, which have a higher probability of malignancy, and the need for chemotherapy depends on the size and postoperative pathologic results to determine whether to add chemotherapy. Generally speaking, mixed ground-glass nodules with large size, unsatisfactory pathological results, and high probability of recurrence can be treated with chemotherapy after surgery to prevent lung cancer, and commonly used drugs include platinum, paclitaxel, etoposide, etc., which need to be used under the guidance of physicians.