Cranial repair is a common procedure in neurosurgery, and there has been a gradual increase in the number of patients with cranial defects, many of whom are unsure of the timing of cranial repair. How long after a cranial defect can cranial repair be performed? The skull is very hard and can normally withstand most general external impacts. However, in reality, we always face a lot of unknowable risks, and the skull is not indestructible under the action of some irresistible factors. For example, some traffic accidents, falling objects, production safety accidents, surgical procedures, etc., may cause skull defects. Once the skull is damaged, it should be repaired in a timely manner, otherwise it may cause damage to the human body, sometimes serious damage, or even fatal damage. When is the best time for cranial repair? Generally speaking, if the trauma is clean and open, without intracranial hypertension, cranial bone repair surgery can be performed immediately; while if the cranial bone is defective due to intracranial hypertension and decompression surgery with debridement flap, it will take about three months for the intracranial pressure to stabilize, and then repair it again. So the timing of cranial bone repair is very important. Clinically, the new polyether ether ketone PEEK cranial bone repair is widely used.