Running after staying up late may lead to sudden death, but it usually occurs in people with organic heart disease.
People with organic heart disease, such as cardiovascular disease, running after staying up late is likely to lead to acute myocardial ischemia, resulting in angina pectoris, myocardial infarction, myocardial cell disorders, triggering malignant arrhythmia after sudden death.
As a result of staying up late for a long time, the organism does not get timely rest, but also activates the renin-angiotensin-aldosterone system, leading to faster heartbeat, higher blood pressure, etc., which further aggravates the burden on the heart after running, thus causing acute sudden cardiac death. In addition after staying up late even if there is no running, it will also damage the cardiovascular, endocrine and so on.
Staying up late is one of the common causes of sudden death, so it is recommended to sleep regularly, and if you feel unwell, you should actively seek medical attention.