Analysis of osteoblastoma

  Osteoblastoma is a bone forming bone tumor, and the pathological classification of WHO 1993 edition is divided into two categories: benign and aggressive/malignant. Because of the controversy and the fact that aggressive osteoblastoma is not essentially different from typical osteoblastoma in morphology and genetics, the 2002 edition deleted aggressive osteoblastoma and classified it as osteoblastoma, both of which are classified into benign tumor classification, but because of the existence of osteoblastoma However, because of the variation of osteoblastoma, osteoblastoma is classified as a subtype of common osteosarcoma.  The incidence of osteoblastoma accounts for about 1% of primary bone tumors and is rare. It is more common in males, with a male to female ratio of 2-3:1, mostly in adolescents aged 10-20 years, and 90% of patients are diagnosed before the age of 30. Especially, spine and sacrum are common. The pain and swelling of varying degrees are common, nerve root compression symptoms may occur, and sometimes pathological fractures may occur. CT, plain films and MRI have characteristic manifestations.  Osteoblastoma is mainly treated by extensive and complete surgical resection, and radiotherapy is feasible for residual or local recurrence. The prognosis of osteoblastoma is good, but there is a certain recurrence rate, about 10-20%, and the more recurrences, the greater the possibility of malignant transformation.