A positive H. pylori antibody indicates the presence of H. pylori infection, or a history of infection with the bacteria. It is common in gastric and duodenal H. pylori infections and can cause gastritis, gastric ulcers and duodenal ulcers, among other diseases. Antibodies to H. pylori can be tested for typing. Positive CagA and VacA suggest that H. pylori is more virulent and pathogenic, and if not previously tested or treated for H. pylori, positive antibodies can be considered for the presence of a presenting infection, and eradication is recommended if it meets the indications for eradication therapy. Treatment of H. pylori currently advocates the use of quadruple therapy, that is, two antibiotics + a proton pump inhibitor + a bismuth agent, such as tetracycline + furazolidone + omeprazole + bismuth. Drug use needs to be adequate, full course of treatment, generally 10-14 days, after 1 month of drug withdrawal for review, C13 or C14 breath test can be performed to determine whether eradication success, after treatment can not be determined by the results of H. pylori antibodies to determine the effectiveness of treatment. People with H. pylori infection should develop good hygiene habits in daily life, correct poor dietary habits, eat more vegetables and appropriate amounts of fruits, maintain a regular lifestyle, quit smoking and drinking and maintain a happy mood, and actively use medication under the guidance of a doctor.