The 13C breath test is the gold standard for screening for H. pylori infection. The rapid urease method, if applied for endoscopy, is not as accurate as the 13C breath test. Gastroscopy to detect H. pylori is to take a partial tissue biopsy for testing, which is an invasive test that more accurately reflects H. pylori infection. Carbon 13 breath test, which is an oral urea capsule followed by a test, this test is more sensitive and accurate. Carbon 13 test is a non-invasive test, this test is relatively fast and relatively inexpensive, suitable for most people, if there are no special circumstances, usually choose carbon 13 for testing. Carbon 13 breath test needs to be performed in the state of fasting, can not have recently used antibiotics or proton pump inhibitors, such as cephalosporins, amoxicillin, omeprazole, etc., there may be false negatives, you should follow the doctor’s instructions for the test.