Tetanus immunoglobulin injections, as well as tetanus antitoxin, are not recommended immediately after drinking alcohol. Although tetanus immunoglobulin does not require a sensitivity test before injection, and the chance of causing an allergic reaction is not high. However, when alcohol is consumed, the chemical reaction between the alcohol and the injected immunoglobulin may reduce the effectiveness of the immunoglobulin and even cause some unwanted adverse reactions, so it is recommended to go to the hospital the next day to have the tetanus immunoglobulin injection after consuming alcohol. Tetanus injections are effective within 24 hours after the trauma, and it is not recommended to drink alcohol again within three days after the tetanus immunoglobulin injection.