Mucocutaneous lymph node syndrome (MCLS), also known as Kawasaki disease, is an acute febrile rash pediatric disease characterized by systemic vasculitis. It is clinically classified as a connective tissue disease. The disease has attracted attention because of the serious cardiovascular lesions that can occur. What are the causes of severe red congestion of the lips and mouth: Herpes labialis: an acute herpetic skin disease caused by the herpes simplex virus. The virus is present in the blisters, saliva and feces of patients, recovered persons or healthy carriers, and is transmitted mainly by direct contact, but also indirectly through saliva-contaminated dishes. Oral mucosal acanthosis nigricans: oral mucosal acanthosis nigricans is mainly hyperpigmentation, hyperkeratosis, rough texture to touch, no abnormalities on the lips. Dry mouth and odor, pulse string, wart-like proliferation as a characteristic skin disease, in which true benign acanthosis nigricans, often with red tongue, yellowish coating, normal diet and diarrhea. It invades the oral mucosa and develops most markedly at puberty. It is indeed rare in the dentistry clinic. Stomatitis: It is an acute or chronic inflammation of the skin and adjacent mucosa in the corners of the mouth due to different factors, mainly prevalent among children, associated with purulent coccus or Candida albicans infection or vitamin B2, vitamin P deficiency, etc. Oral cancer: 8.7% of men and 2.3% of women have metastatic skin cancer from the oral cavity. Almost all of them are squamous cell carcinoma skin metastases located on the skin of head and neck. Ulcerative necrotizing stomatitis: a severe form of oral necrotizing lesion caused by infection with Spirochaete vincent or Clostridium perfringens. Mouth erosion: The name of mouth erosion was first found in the Nei Jing. The Su Wen Qi Symposium says: “The bladder moves heat to the small intestine, and the li intestine is inconvenienced, and the upper part of the mouth is celiac.” This disease has also been discussed by doctors in subsequent generations. It occurs in children, and is more common in infants within one year of age or in infants less than one month old, and is also known as thrush, swallow sore, white sore, and snow sore. In adults, it is often secondary to typhoid fever, large burns or scalds, diarrhea, diabetes mellitus, primary immunodeficiency, and long-term heavy use of antibiotics. Sigmoid colostomy parastomal hernia: colostomy is a treatment for malignant colorectal tumor, trauma and neonatal anus and rectal malformation. After combined abdominal perineal resection (Mile), two pores can be formed in the abdominal cavity: the pore between the stoma intestinal tube and the left abdominal wall and the pelvic floor peritoneum formed by improper suturing or abdominal distension, and the small intestine slides into these two pores to form a sigmoid colon Parastomal hernia (postsigmoidostomic hernia). Sigmoidostomic hernia is a complication after colostomy and can occur in the early postoperative period.