The common causes of lymph node pain in the left chin of patients are mainly the following: a. When acute infection occurs in the left submaxillary soft tissue or is accompanied by acute pharyngitis or acute purulent tonsillitis, it can cause enlargement and hyperplasia of the left chin lymph nodes with obvious painful symptoms. Patients can take oral amoxicillin and levofloxacin tablets for active anti-infection treatment. After the local inflammation has completely subsided, the swollen lymph nodes in the left chin can gradually subside, and the prognosis is relatively good. Second, if malignant tumor such as malignant tumor of thyroid gland, malignant tumor of oral cavity, malignant tumor of nasopharynx, tumor cells invade to the lymph nodes under the left jaw causing swollen and painful lymph nodes, even if surgery is performed to remove the malignant tumor and lymph nodes are cleared, the malignant tumor will still recur after surgery and the prognosis is relatively poor.